Publications

  • 2016

Design, synthesis, and pharmacological Evaluation of 2(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)Naryl Propanamides as Novel Smoothened (Smo) Antagonists

Liu, G.; Xue, D.; Yang, J.; Wang, J.; Liu, X.; Huang, W.; Li, J.; Long, Y.-Q.*; Tan, W.;* and Zhang, A.*

J. Med. Chem.2016, 59, 11050-11068.







GPR40 agonists for the treatment of type 2 diabetes mellitus: the biological characteristics and the chemical space.

Chen, C.; Li, H.; Long, Y.-Q.*

Bioorg. Med. Chem. Lett.2016, 26(23), 5603-5612.





Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency.

Cheng, Y.; Shen, J.; Peng, R.-Z.; Wang, G.-F.; Zuo, J.-P.*; Long, Y.-Q.*

Bioorg. Med. Chem. Lett.2016, 26, 2900-2906.